By Kim McDonald, 22 January 2023
Percoll gradients can be used to isolate specific cells, subcellular particles, and viral particles via centrifugation based on their individual densities. Gradients can be pre-formed before the isopycnic separation of cells at low speeds. However, viruses and subcellular particles generally will not efficiently separate on pre-formed gradients. In this case, in situ gradient preparation is needed where the sample is diluted in the Percoll solution prior to centrifugation; particles are separated simultaneously to gradient formation.
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By Kim McDonald, 05 October 2022
Though precise temperature control may not be required for many applications, some analytes are temperature-sensitive and require stable temperature control. Refrigerated centrifuges counteract the temperature fluctuations that occur during centrifugation, making them suitable for temperature-sensitive analytes.
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By Doran Amos, 10 September 2021
Platelet-rich fibrin (PRF) can be prepared from a patient's blood to aid in wound healing, but how can the quality of the PRF be maximized? In this article, we summarize the latest evidence about how best to prepare PRF using a centrifuge.
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By Doran Amos, 17 August 2021
Platelet-rich plasma (PRP) is widely used to promote tissue repair and bone growth—but what is the best way to prepare it? In this blog, we guide you through the latest research and recommendations on optimizing the collection, centrifugation and storage of PRP...
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By Aimee O'Driscoll, 04 July 2021
Want to create your own centrifuge? We review a range of "instructables" including models using paper and string, a salad spinner, and a Dremel tool.
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By Aimee O'Driscoll, 05 December 2019
We discuss the main factors you need to consider when purchasing a lab centrifuge, including maximum RPM and RCF, temperature range, and warranty options.
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By Aimee O'Driscoll, 24 October 2019
We reveal the steps to take to keep your lab centrifuge in good working order and prolong the life of the unit.
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By Aimee O'Driscoll, 18 July 2019
When it comes to centrifuge rotors, there are lots of options to choose from. We explain the main areas you need to consider, including centrifuge and vessel compatibility and rotor style.
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By Aimee O'Driscoll, 28 March 2019
We explain the relationship between RPM and RCF, which parameter is most important in centrifugal applications, and how to convert between the two.
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By Aimee O'Driscoll, 12 March 2019
Incorrectly balanced tubes can damage a centrifuge and pose a safety risk to lab personnel. We discuss best practices for balancing samples in a lab centrifuge.
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By Aimee O'Driscoll, 19 December 2018
If used incorrectly, a lab centrifuge can be a dangerous piece of equipment. We explain the steps you can take to mitigate the risks involved in running a lab centrifuge.
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